Symbol
Name
ID

Fyn
Fyn proto-oncogene
MGI:95602

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	EEG abnormality	Delusion	Schizophrenia	Hallucinations	Negativism	Social and occupational deterioration
Disease(s) Associated with FYN
schizophrenia

Mouse Phenotypes

increased susceptibility to pharmacologically induced seizures

abnormal seizure response to electrical stimulation

abnormal kindling response

audiogenic seizures

tonic seizures

decreased corpus callosum size

abnormal hypothalamus morphology

abnormal hippocampus morphology

abnormal dentate gyrus morphology

abnormal hippocampus layer morphology

abnormal hippocampus pyramidal cell layer

abnormal hippocampus pyramidal cell morphology

ectopic hippocampus pyramidal cells

increased hippocampus pyramidal cell number

abnormal somatosensory cortex morphology

abnormal stratification in cerebral cortex

abnormal olfactory bulb morphology

abnormal optic nerve morphology

abnormal myelination

abnormal excitatory postsynaptic potential

reduced long-term potentiation

Availability

Mouse Genotype

Fyn^tm1Fam/Fyn^tm1Fam

Fyn^tm1Sor/Fyn^tm1Sor

Fyn^tm1Sor/Fyn^tm1Sor
Tg(Camk2a-Fyn)1Kndl/0

Fyn^tm1Yik/Fyn^tm1Yik

Fyn^tm1Sor/Fyn⁺
Tg(Camk2a-Fyn-531)1Nko/0

Tg(Camk2a-Fyn-531)1Nko/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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